Personalized prediction of lymph node metastasis in papillary thyroid microcarcinoma - a nomogram and web calculator: Open Science and Comparative Benchmarking

Transparent materials and comparable benchmarks are required to reproduce a result, locate disagreement, and determine whether improvements persist under a shared protocol. This structured evidence review evaluates "Personalized prediction of lymph node metastasis in papillary thyroid microcarcinoma: a nomogram and web calculator" alongside nine author-disjoint, topically matched publications in clinical risk prediction. It compares construct definitions, evaluation choices, operating assumptions, and reported limitations instead of treating bibliographic similarity as empirical equivalence. Viewed through open science and comparative benchmarking, the map separates claims supported by the available record from questions that still require full-text extraction, replication, or new experiments. The synthesis is interpretive rather than meta-analytic and therefore does not present a pooled effect estimate or a new causal result. The resulting agenda calls for reusable protocols, versioned artifacts, common outcome definitions, and transparent reporting of unsuccessful replications.

1. Zhang, W., Zhu, J., Zhang, Y., Sun, L., Wang, K., Dong, Y., Yan, W., Yu, X., Zhang, Y., Jia, W., Wang, W., & Shang, A. (2025). Personalized prediction of lymph node metastasis in papillary thyroid microcarcinoma: a nomogram and web calculator. Scientific Reports, 15(1), 45288. https://doi.org/10.1038/s41598-025-28483-8 DOI
2. Qiu, P., Guo, Q., Pan, K., & Lin, J. (2024). Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma. BMC Cancer, 24(1). https://doi.org/10.1186/s12885-024-12004-3 DOI
3. Sun, Y., Sun, W., Xiang, J., & Zhang, H. (2023). Nomogram for predicting central lymph node metastasis in T1-T2 papillary thyroid cancer with no lateral lymph node metastasis. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1112506 DOI
4. Min, Y., Feng, Y., Xiang, K., Chen, H., Wang, X., & Yin, G. (2021). A Nomogram Predicting Central Lymph Node Metastasis for Patients with Papillary Thyroid Cancer. . https://doi.org/10.21203/rs.3.rs-182268/v1 DOI
5. Xiao, Y., Zhou, P., Zheng, Y., Zheng, C., Liu, G., & Liu, W. (2021). A Nomogram for Predicting Lateral Lymph Node Metastasis in Cases of Papillary Thyroid Micro-Carcinoma with Suspected Lymph Node Metastasis. Oncologie, 23(2), 219-228. https://doi.org/10.32604/oncologie.2021.016480 DOI
6. Zhou, J., Zhao, B., Liu, L., & Shi, K. (2024). A nomogram for individualized prediction for cervical lymph node metastasis of papillary thyroid carcinoma. Gland Surgery, 13(11), 1965-1976. https://doi.org/10.21037/gs-24-277 DOI
7. Zhao, W. (2023). A nomogram prediction for the metastasis of central lymph node in papillary thyroid carcinoma: One-center retrospective report. Asian Journal of Surgery, 46(9), 3916-3917. https://doi.org/10.1016/j.asjsur.2023.03.174 DOI
8. Zhao, D., Li, W., & Zhang, X. (2024). Development and validation of a nomogram for preoperative prediction of ipsilateral cervical central lymph node metastasis in papillary thyroid cancer: a population-based study. Gland Surgery, 13(4), 532-543. https://doi.org/10.21037/gs-23-478 DOI
9. Feng, H., Chen, Z., An, M., Chen, Y., & Chen, B. (2023). Nomogram for preoperative prediction of high-volume lymph node metastasis in the classical variant of papillary thyroid carcinoma. Frontiers in Surgery, 10. https://doi.org/10.3389/fsurg.2023.1106137 DOI
10. Lu, Y., Qian, K., Fei, M., Guo, K., Shi, Y., & Wang, Z. (2022). A prognostic nomogram for papillary thyroid cancer lymph node metastasis based on immune score. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.993856 DOI